Please kindly advise me cause am depressed and confused and may commit suicide

Firstly I will like to apologize for any errors made while typing, and I am seriously in need of ur advice and criticism.
My name is Stanley (not real names) married for 4years with two Lovely kids both female with d eldest at age 4. Trust me I cherish and love my family. I am a graduate while my wife dropout from the university cause of some money issues her single mother had while she was sick. After our first child I made sure she got admitted to a polytechnic and thankful she just rounded up her N.D all expenses paid by me, with high hopes of Getting admitted for her HND.
The problem started after our first child, my wife attitude towards sex changed totally, she would never let me touch her or play with her, calling her pet names will usually end in quarrel, I spoke with her severally, pleaded and beg her most times but her attitude never changed, she made me feel like I meant nothing to her, yet she will always fight with me whenever ever she suspects I have a girlfriend, fights with any female that comes close to me through calls or chats, she even went as far as beating up a lady that needed my help thinking I was dating her.
Fast forward to recently, her mom who is a single mother relocated to stay with us, and during her stay we had some misunderstanding about money issues, (note both me and my wife are gainfully employed in the ratio of 10:4, but 60% of my wife’s salary goes to her mum while she spends the rest 40% anyhow she likes) during the money issues a friend of hers came and told both of them that she saw me flirting with a lady.
And without hearing my own side of the coin my mother in-law rained curses on me , reported me to all her family members and left my house angrily, two days later my wife took our children and left my house while I was in the office, I called about her whereabout and she said she won’t tell me and she said I will hear from her family soon, her mom called a family friend saying she will sue me.
It’s been one week now and I don’t know their whereabouts of my kids.
Should I report to the police or what?
Note I have apologized to my wife for the crime I didn’t commit yet it seems they want a bigger pound of flesh.
Please kindly advise me cause am depressed and confused